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Epidemiology and treatment outcomes of bacterial and fungal keratitis in Minia Governate, Egypt

Poster Details

First Author: A.Abdelghany EGYPT

Co Author(s):    N. Mabrouk   M. Osman   K. Mourad   M. Abdelhakeem           

Abstract Details

Purpose:

The purpose of the study is to determine the microbiological aetiology, epidemiological factors, and clinical profile and treatment outcomes of infective keratitis in Ophthalmology department, Minia University. Egypt.

Setting:

Ophthalmology department. Faculty of Medicine, Minia University, Minia, Egypt.

Methods:

Prospective, non-randomized, observational clinical study, including 150 patients with mean age 30 (range 2 to 80 years), 93 patients (62 %) were males and 57 (38%) were females, clinically diagnosed as infective corneal ulcer. A total of 150 corneal scrapings were obtained from patients attending the Ophthalmology Department – Faculty of Medicine. Minia University, Minia, Egypt, during a period of 18 months from September 2018 to February 2020. Scrapings were subjected to staining and culture for bacterial and fungal pathogens; bacterial and fungal growth were identified by standard laboratory procedures.

Results:

Corneal trauma by a vegetative matter was the main risk factor associated with infective keratitis in 90 cases (60%). Culture was positive in 69 cases (46%), of which 45 cases were fungal (65.22%), 22 case were bacterial (31.88%) and 2 cases were mixed bacterial and fungal (2.90%), smear was positive in 73 cases (48.67%). Aspergillus species was the commonest fungal species isolated in fungal keratitis. 142 cases (94.66 %) healed completely with scar. Only 8 cases (5.34%) required evisceration due to aggressive presentation from the start.

Conclusions:

Fungal keratitis was the commonest type in cases attending to our department. Adequate diagnosis, management and follow up helped in achieving high successful curative outcomes.

Financial Disclosure:

None

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