ePoster

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Title:

Evaluation of the ganglion cell and inner plexiform layer in children with optic neuritis

Poster Details

First Author: G. Fijałkowska- Cmokowicz POLAND

Co Author(s):    E. Filipek   A. Tronina   B. Wójcik-Niklewska   D. Barchanowska           

Abstract Details

Purpose:

The aim of the study is to assess the effect of the acute and past optic neuritis (ON) on the thickness of ganglion cells layer and inner plexiform layer (GCL+IPL) in children in the Optical Coherence Tomography (OCT) of the macula and optic nerve.

Setting:

Paediatric Ophthalmology Department, University Clinical Center prof. K. Gibi?ski of Medical University of Silesia in Katowice, Poland

Methods:

In each of the children from the study and comparative group we measured: distance visual acuity (VA), near vision (Sn), intraocular pressure, biometry of the eye . We also performed anterior and posterior eye segment examination in the slit lamp (before and after puppil dilatation), examination of the average, minimum thickness of the GCL + IPL and in six individual segments of the central retina, examination of the average thickness of the RNFL layer, and the Visual Evoked Potentials (VEP) examination only in the study group.

Results:

We found significant improvement in VA in the study group after recovery of ON. Significant reduction was found in the average, upper temporal, upper nasal, lower temporal and lower nasal GCL + IPL thickness in the measurements taken after recovery comparing to those taken during the ON. Similar results were reported for average RNFL thickness. Significantly higher values were noted for all parameters in the control group, compared to the parameter values in the study group during optic neuritis, excluding the mean RNFL thickness.

Conclusions:

After ON in children the thickness of the GCL+IPL decreases only in some segments of the central retina in the OCT. The greatest decline occurs in the upper middle and upper nasal segments. Measurement of the GCL+IPL thickness in individual segments in the OCT is sensitive and useful parameter in the diagnosis of structural damage to the visual pathway after ON in children.

Financial Disclosure:

gains financially from competing product or procedure, travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, receives non-monetary benefits from a company producing, developing or supplying the product or procedure presented, receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, is employed by a competing company, has significant investment interest in a company producing, developing or supplying product or procedure presented