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Comparison of Physical Properties and Annual Costs of Two Multi-dose Eye Drops Containing Latanoprost

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First Author: I.Tuncer TURKEY

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Abstract Details

Purpose:

To compare of drop size, number of drops per milliliter, number of drops in bottle, bottle volume and annual costs of two multi-dose eye drops containing latanoprost.

Setting:

Alfa Medical Center, Izmir, Turkey

Methods:

Xalatan and Latapol eye drops available in Turkey were included in this study. The first 10 drops size was measured with a micropipette and the average of the drop size was found. The repeatability coefficient of the first 10 drops size was calculated. Number of drops per milliliter, number of drops in bottle and bottle volume were measured in a graduated cylinder calibreted in increments of 0.1 ml. The annual cost was calculated based on the number of drops in the bottle.

Results:

The drop size was 27.56 µl and 27.66 µl for Xalatan and Latapol, respectively(p=0.729). The lowest-highest drop size and repeatability coefficient for Xalatan were 26-29µl and ±1.39µl, respectively, 25-30µl and ±1.93µl for Latapol. The number of drops per milliliter, the number of drops in the bottle and the bottle volume for Xalatan were 36.27 drops, 99 drops and 2.77ml, respectively, 35.47 drops, 93.66 drops and 2.66ml for Latapol(p=0.672, p=0.007 and p =0.008, respectively). The cost per drop and the annual cost for Xalatan were 0.2101 ₺ and 153.37 ₺ respectively, 0.2220 and 162.11 ₺ for Latapol (p=0.031 and p=0.010, respectively).

Conclusions:

The number of drops in bottle and bottle volume of Xalatan is significantly higher than Latapol, which causes the annual cost of Xalatan to be significantly lower.

Financial Disclosure:

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