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Morphological Changes in Schlemm’s Canal after Lens Extraction in Primary Angle-Closure Glaucoma

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First Author: N.Alagoz TURKEY

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Abstract Details

Purpose:

To evaluate the morphological changes of Schlemm’s canal (SC) in eyes with primary angle-closure glaucoma (PACG) after lens extraction using a swept-source optical coherence tomography (SS-OCT).

Setting:

Beyoglu Eye Training and Research Hospital, Istanbul, Turkey

Methods:

The SC of 17 eyes of 17 patients (mean age 58.0±7.2 years, 12 male/5 female) with chronic PACG that underwent lens extraction by phacoemulsification surgery was analyzed by anterior segment SS-OCT prior to surgery and at week 1 and month 1 after surgery. The SC length was measured as meridional and coronal diameters in the temporal regions of all subjects.

Results:

Mean intraocular pressure preoperatively and at week1 and month1 was 25.1±9.6, 14.2±4.4 and 15.05±5.1 mmHg, respectively (Pw1=0.002, Pm1=0.004). The rate of observable SC prior to surgery was 59%, while it was 88% at week 1 and 100% at month 1 for temporal sections. The mean meridional diameter of SC was measured as 324.2±72.9, 355.5±63.8 and 352.3±56.9 μm preoperatively and at week 1 and month1, respectively (Pw1=0.263, Pm1=0.04). The mean coronal diameter was measured as 9.5±3.7, 22.0±10.6 and 18.7±9.4 μm preoperatively and at week 1 and month1, respectively (Pw1=0.001, Pm1=0.001).

Conclusions:

In chronic PACG, a significant increase especially in the coronal diameters of SC was observed following cataract extraction. The expansion of the SC in the postoperative period also resulted in the higher observable SC rates by SS-OCT.

Financial Disclosure:

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