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Characteristics of Corneal Topography and Densitometry in Offspring of Patients with Keratoconus

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First Author: H.Kiziltoprak TURKEY

Co Author(s):    K. Tekin   P. Kosekahya                 

Abstract Details

Purpose:

To investigate the corneal topographic, topometric and densitometric characteristics in offspring of keratoconus patients that have virgin corneas with no previously known ectasia.

Setting:

Health Science University, Ulucanlar Eye Training and Research Hospital.

Methods:

This prospective study included 22 eyes of 11 offspring of keratoconus patients and 38 eyes of 38 healthy controls that had no known familial keratoconus were selected for study. All subjects underwent topographic, topometric, tomographic (Belin-Ambrósio Enhanced Ectasia Display III) and densitometry analyses via a Pentacam HR rotating Scheimpflug camera (Oculus, Germany, version 1.20r.98).

Results:

Clinical keratoconus was diagnosed in 1 of 11 offspring of keratoconus with patients and excluded from the study. There were no statistically significant differences in K1, K2 and Kmax values, however the thinnest corneal thickness and posterior surface elevation values were statistically significantly different (p=0.003 and p=0.039, respectively). Except for Dt (p=0.003), the other Belin/Ambrósio indicators including Df, Db, Dp, Da and final D showed no significant differences (p>0.05). Among the topometric parameters, only keratoconus index (KI) was significantly different between groups (p=0.034). Among the corneal densitometry parameters, all layers of 0-2 and 2-6 zones were significantly different between groups.

Conclusions:

The anterior segment parameters measured by Pentacam HR of the offspring of patients with keratoconus showed significant alterations in posterior elevation, thinnest corneal thickness, Dt, KI and central zone corneal densitometry values.

Financial Disclosure:

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