First Author: M.Karageorgieva BULGARIA
Co Author(s): R. Hristova
Purpose:
To study the frequency of risk factors for progression among glaucoma patients treated in the clinic
Setting:
: Queen Joanna University Hospital - Ophthalmology Department - Sofia, Bulgaria
Methods:
The research is retrospective and includes 466 patients with glaucoma and ocular hypertension treated in the clinic from 01.01.2010 to 01.07.2011.
All patients have been obligatory fully examined as follows: visual acuity with correction, biomicroscopy, gonioscopy of iridocorneal angle, IOP fluctuation, fundoscopy, perimetry, CCT. The main risk factors that may influence the progression of glaucoma have been examined.
Results:
Risk Factors are examined among 466 patients with glaucoma (100%)
1. Age - 412 patients (88.4%).
2. High IOP - 446 patients (100%).
3. Myopia - 75 patients (16%).
4. Family history - 20 patients (4.3%).
5. CCT (measured in 100 patients) - 65 patients (65%).
6. Arterial hypertension - 230 patients (49.4%).
7. Vascular pathology - 101 patients (21.7%).
8. PEX - 92 patients (19.7%.)
9. Diabetes ? - 35 patients (7.5%).
10. Others* 92 patients (19.7%).
*Over 30 other diseases are risk factors and are grouped as “others”: Endocrine (without diabetes) – most commonly Hashimoto thyroiditis; Autoimmune – RA; Bone/tendon degenerations – arthroses.
Distribution by gender: Women: 330 patients (70.8%); Men: 136 patients (29.2%).
Distribution by age:
0-18 years: 1 patient (0.2); 19-45years: 46 patients (9.9%); 46-65 years: 54patients (11.6%); Over 66 years: 365 patients (78.3 %).
Conclusions:
According to the results of our study the frequency of glaucoma is higher in women and in the age over 45.
There is a big variety of risk factors as trigger mechanism for glaucoma as is the risk of progression.
The most common risk factors are: high IOP, age, CCT, arterial hypertension, PEX, vascular pathology, etc.
A fact of interest is the frequency of autoimmune diseases, associated with glaucoma, which supports the presence of similar mechanisms for development of these two pathologies.
There is a hypothetic connection between glaucoma and Hashimoto’s disease.
Some bone tendon degenerative diseases also show association with the development of glaucoma.
Financial Disclosure:
None