First Author: A.El Habbak EGYPT
Co Author(s): A. Fayed M. Abdelzaher
Purpose:
To identify the correlation between diabetic retinopathy (DR) and peripapillary retinal nerve fiber layer thickness detected by OCT.
Setting:
: A prospective study including diabetic patients (20 eyes) and non-diabetic control subjects (10 eyes).
Methods:
Baseline optical coherence tomography was employed to measure retinal thickness in the macula (superior, inferior, nasal, temporal and central) and the peripapillary zone (superior, inferior, nasal, and temporal). Nine baseline parameters were correlated with the DR stages identified by fluorescein angiography.
Baseline retinal nerve fiber layer thickness was compared between groups of patients requiring panretinal photocoagulation (PRP) within 6 months (PRP group) and patients not requiring PRP (No-PRP group).
Results:
Macular and peripapillary retinal nerve fiber layer thicknesses in diabetic subjects were significantly greater than that in normal controls (p<0.05). All retinal thickness parameters, and particularly peripapillary circular scans, tended to increase with increasing DR severity (p<0.05). The baseline thicknesses of the peripapillary circular scans were greater in the PRP group than in the no-PRP group (p<0.05).
Conclusions:
Peripapillary retinal nerve fiber layer thickness may prove to be a useful criterion for DR severity and may also serve as an indicator of disease progression.
Financial Disclosure:
None
