First Author: H.Solodkova RUSSIA
Co Author(s): I. Melikhova
Purpose:
To evaluate corneal collagen crosslinking results in treatment of progressive keratoconus basing on findings of anterior segment optical coherent tomography
Setting:
: S.Fyodorov Eye Microsurgery Federal State Institution Volgograd branch
Methods:
there were followed 25 patients (25 eyes) with progressive keratoconus of the I-III degree who underwent CXL with a customized excimer laser deepithelialization to the depth of 2/3 of the epithelial layer. Mean patients’ age was 26±13 years. Follow-up period equaled 1, 3, 6 and 12 months. All patients were subject to an extended ophthalmological examination with anterior segment OCT (OCT RS-3000, Nidek, Japan). Preoperative findings were as follows: NCVA averaged 0,15 ± 0,03, BCVA – 0,45 ± 0,06, mean pachymetric value - 465,5 ± 25 µm, mean corneal epithelium thickness - 55 ± 0,5 µm.
Results:
one month post-surgically OCT revealed a demarcation line in corneal stroma. NCVA averaged 0,2 ± 0,04, BCVA equaled 0,3 ± 0,07. Six-months postoperatively OCT showed that demarcation line had achieved its maximum optical density, first indications of stromal compaction emerged. NCVA equaled 0,2 ± 0,05, BCVA - 0,6 ± 0,05, mean pachymetric value - 455,5 ± 2,0 µm, mean corneal epithelium thickness - 55 ± 0,5 µm. 12 months post-surgically a moderate hyperplasia of corneal epithelium was observed. NCVA equaled 0,4 ± 0,05, BCVA - 0,7 ± 0,06, mean pachymetric value - 475,5 ± 2,0 µm, mean corneal epithelium thickness - 55 ± 0,5 µm.
Conclusions:
OCT, performed at different follow-up periods revealed that CXL induced various morphological changes such as epithelial hyperplasia, demarcation line, corneal stroma compaction. Improvement of visual functions and clinical parameters corresponded to intensity of morphological changes
Financial Disclosure:
None
