First Author: J.Gonz SPAIN
Co Author(s): F. G J. Zarallo Gallardo R. Cobo Soriano
Purpose:
To measure the impact of tamsulosin intake on six postoperative cataract surgery complications (toxic anterior segment syndrome, rebound uveitis, retinal detachment, macular edema, postoperative endophthalmitis and posterior capsule opacification).
Setting:
: Ophthalmology Unit of Hospital del Henares (Madrid, Spain)
Methods:
COHORT RETROSPECTIVE STUDY. Eight hundred and one eyes submitted to cataract surgery from March 2, 2009 to February 28, 2010. Clinical charts were reviewed during July 2012. Patients were divided in two groups (exposed and unexposed to tamsulosin). Cumulative incidence of toxic anterior segment syndrome, rebound uveitis, retinal detachment, macular edema, posterior capsule opacification and postoperative endophthalmitis were compared in both groups. Posterior capsule opacification was also studied using Kaplan-Meier method. Survival curves were compared using log-rank test.
Results:
Rebound uveitis was more common in the tamsulosin consumer group (RR=2.60; CI:1.28-5.28). Retinal detachment, macular edema (RR=3.70; CI: 0.98-14.06) and posterior capsule opacification (RR=0.84; CI:0.52-1.35) had a similar incidence in both groups. No difference in posterior capsule opacification in the survival plots could be demonstrated between consumers and no consumers (p=0.741). None cases of postoperative endophthalmitis or toxic anterior segment syndrome, were observed in any of the groups.
Conclusions:
Tamsulosin consumption in this cohort was associated with a higher risk of rebound uveitis but the other five studied complications had a similar incidence in both groups.
Financial Disclosure:
None
