Age in overcorrection laser subepithelial keratomileusis (LASEK) after mitomycin C (MMC)

Poster Details

First Author: JaimeGarrido linares SPAIN

Co Author(s):    Jose Luis Ramos Navarro   Cristina Perez Casaseca           

Abstract Details

Purpose:

Study if overcorrection and determine whether the degree of this is correlated with age in patients undergoing laser subepithelial keratomileusis ( LASEK ) after topical application of 0.02% Mitomycin C (MMC) .

Setting:

: Clinica Baviera. Instituto Oftalmologico Europeo.Spain.Málaga

Methods:

A retrospective study of 180 eyes undergoing LASEK surgery with a follow-up of 12 months. All eyes were treated with an excimer laser , Technolas 100 Z . Inclusion criteria : spherical equivalent (SE ) treaty between -1.5 and -9 D , central corneal thickness > 460 microns , without prior systemic or ocular pathology . There were two groups of 90 eyes one of which was applied topically MMC 0.02 % for 15 seconds after the laser treatment using methylcellulose sponge 8 mm in diameter . After washing with physiological saline and the corneal epithelium replenishment placed a contact lens was removed from the 5th and 7th day. The group that the MMC was applied in turn was divided into 2 groups of 45 eyes each depending on age. One of ≥ 40 years and other <40 years. We studied whether there overcorrection after using the MMC and if related to the patient's age .

Results:

In the group of 90 eyes that was not applied MMC SE treated medium was -5.07 ± 0.87 D and -6.85 ± 0.78 D in the group to which MMC was applied . Within this group that we employ MMC the SE treated in the ≥ 40 years group was -6.42 ± 0.34 D and -7, 02 ± 0.45 D in the <40 years . At 12 months, the SE is 0.58 ± 0.23 D in the MMC group , with age group of 0 , 67 ± 0.25 in the group ≥ 40 years and 0.34 ± 0 , 12 D in the group <40 years and 0.13 ± 0.11 D in the control group . None of the eyes developed haze . Statistically significant differences ( P < 0.05 ) between the group in which we use MMC and control groups and between the two age subgroups .

Conclusions:

The MMC 0.02 % for 15 seconds induces an average overcorrection of 0.58 ± 0.23 D , being higher (0.67 ± 0.25 D ) in patients older than 40 years than in those younger than 40 years (0.34 ± 0.12 D). The MMC 0.02 % for 15 seconds is effective against the development of haze . FINANCIAL INTEREST: NONE