Safety and efficacy of stand-alone CyPass Micro-Stent implantation in patients

Poster Details

First Author: MagdaRau GERMANY

Co Author(s):    Tsontcho Ianchulev   J. Garcia-Feijoo   Salvatore Grisanti   Pravoslava Guguchkova     

Abstract Details

Purpose:

Evaluate the safety and outcomes of suprachoroidal micro-stent implantation as a treatment for open-angle glaucoma,

Setting:

: Multi-site clinical study in Europe and Canada.

Methods:

In prospective, multicenter interventional case series (DUETTE study),the CyPass Micro-Stent (Transcend Medical, Inc, Menlo Park, CA)was implanted in 65 subjects for whom medical therapy was insufficient to control intraocular pressure into the supraciliary space through a 1.5 mm incision. Safety data, including adverse events, complications, intraocular pressure, and medications, are reported up to 12 months postoperative.

Results:

68% of subjects were on 2 or more medications and all had a baseline medicated IOP ≥ 21 mmHg. Mean medicated IOP at baseline was 24.3 mmHg. There were no cases of suprachoroidal hemorrhage, bleb-related complications, retinal complications or hypotony maculopathy. At 12 months after surgery, mean IOP was 15.2 mmHg with a 41% reduction in IOP from baseline. 86% of patients had a >20% reduction in IOP with a concomitant reduction or no change in IOP-lowering medications.

Conclusions:

The supraciliary CyPass Micro-Stent provided safe and sustained IOP reduction in patients with primary open-angle glaucoma. FINANCIAL INTEREST: NONE