Posters

Drug resistant Acremonium kiliense keratitis in contact lenses wearers

Poster Details

First Author: R.Strupaite LITHUANIA

Co Author(s): A. Makselis   D. Petroska   R. Asoklis              

Abstract Details

Purpose:

To report the predisposing risk factors, clinical presentation, management and therapeutic outcomes of fungal keratitis caused by Acremonium kiliense.

Setting:

Center of Eye Diseases, Vilnius University, Lithuania

Methods:

This is a retrospective study of cases with Acremonium kiliense fungal keratitis that presented to our tertiary referral center between September 2013 and January 2016. Patient demographic and clinical details were determined and reported.

Results:

Four cases of fungal keratitis from Acremonium kiliense were identified in four patients (two males, two females). The mean age of the patients was of 45.75 years (range 23-72). All patients had a history of contact lens (CL) wear, prolonged antibiotics and steroid use, one patient had trauma with beetle. Four cases were unresponsive to initial treatment (0.15% amphotericin B) and three of four needed treatment with 1% voriconasole. All patient underwent penetrating keratoplasty. One patient eventually underwent enucleation.

Conclusions:

The most common risk factors for Acremonium fungal keratitis are CL wear, prolonged antibiotics and steroids use. When a corneal lesion is found to be unresponsive to the initial treatment, penetrating keratoplasty should be considered.

Financial Disclosure:

None