Refractory anisometropic amblyopia in children: a cross sectional study

Session Details

Session Title: Moderated Poster Session: Miscellaneous
Session Date/Time: Saturday 10/02/2018 | 14:00-15:00
Paper Time: 14:08
Venue: Poster Area


First Author: M.Ghasempour IRAN
Co Author(s): S. Ramin  M. Aghazedehamiri  S. Tabatabaei           

Abstract Details

Purpose:

The aim of this study was to answer that why in some children of anisometropic amblyopia, the amblyopia is treated merely by refractive error correction, whereas in others correction along with active and inactive treatment and why in a number of children, despite the same symptoms, the amblyopia is not treated by the same treatment measure?

Setting:

This study has been conducted at Shahid Beheshti University of Medical Sciences, Tehran, Iran at 2016.

Methods:

In this descriptive-analytical study, 114 children with anisometropic amblyopia with mean age of 7.35±1.61 without strabismus and organic pathology were included. The children divided into two groups, the control group (non-resistant to treatment with best corrected visual acuity (BCVA) ≥ 0.9, Anisoaxial Max. 1 milimeter, AnisoIOL Max. 3.75 and anisometropia Max. 3.50 diopter); and the subject group (resistant to treatment with BCVA ≤ 0.8; as BCVA of the fellow eye was 20/20, Anisoaxial higher than 1 milimeter, AnisoIOL Min. 4.00, and Anisometropia Min. 3.75 diopter). The examination in both groups were assessment of microtropia, cycloplegic refraction, and BCVA.

Results:

In total, 103 children (90.35%) were nonresistance to treatment and 11 children (9.64%) were resistance to treatment. In terms of amblyopia intensity, 89 children had mild amblyopia, 19 children were moderate amblyopia and 6 children were deep amblyopia (VA<0.16). A statistical significant difference were between the two groups in mean axial length (P=0.036), the anterior corneal power (p=0.010) in amblyopic eye, refractive error (p<0.001), anisoaxial (p<0.001), anisoIOL (P<0.001) and anisometropia (p<0.001). All children in the subject group revealed minimum 4.00 diopter anisoIOL. A statistically significant relationship found between maximum 1 millimeter anisoaxial and the control group, anixoacial more than 1 millimeter, and the subject group (P<0.001). We found a negative linear relationship with r2=0.774, between anisoaxial and BCVA; and a positive linear relation between anisoaxial and anisometropia with r2=0.835. The correlation between refractive error and cornea power was not significant (p=0.559).

Conclusions:

As ansiometropia becomes more intensive, the anisoaxial degree increases and by increasing the anisoaxial, BCVA worsens; and later, higher resistance to treatment may appears. All refractory cases revealed anisoaxial higher than 1 millimeter therefore, over than 1 millimeter anisoaxial may be considered as resistance to treatment.

Financial Disclosure:

None